Of all the discoveries and breakthroughs around COVID-19, one particular study caught our attention. While vaccination remains as the best way to prevent COVID-19, researchers recently conducted a study that demonstrated promising results with a specific seaweed extract as a preventative measure against the disease. Even the World Health Organization recognized the potential of seaweed as a prophylactic or therapeutic solution as being noteworthy.
Though we’re familiar with the uses of seaweed as an antiviral agent, this exciting finding left us wanting to know more. So here’s what we found out about the uses of seaweed extract against COVID-19.
Stopping the Spread of COVID-19
In the study conducted by the Center of Biotechnology and Interdisciplinary Studies (CBIS) at Rensselaer Polytechnic Institute, scientists were exploring alternatives to remdesivir. They were curious to see if any of five specific sulfated polysaccharides (two fucoidans found in natural seaweed and three variants of heparin) could outperform the Ebola antiviral medication against SARS-CoV-2.
The idea was to see if these compounds could work as a decoy, the way remdesivir does to trap and neutralize the virus. When the spiky proteins on SARS-CoV-2 latch onto the appropriate human cell receptors, they can insert their DNA into the host and hijack the cell functionality for their own replication. Researchers were hopeful that the structure of these polysaccharides was close enough to human cells to stop the spread of the virus.
The tests showed that one of the fucoidans (RPI-27) had real potential as an alternative therapeutic. In the dose response study conducted by CBIS, RPI-27 inhibited viral infectivity with greater potency than remdesivir and also produced no cellular toxicity – even when the highest concentrations of the fucoidan were tested.
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